Biacore® Sensor Chip CM5 - Attach proteins, nucleic acids, carbohydrates or small molecules

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The Biacore Sensor Chip CM5 is the most versatile chip available and the first choice for immobilization via -NH2, -SH, -CHO, -OH or -COOH groups.

Indeed it supports a wide range of immobilization levels and permits to attach proteins, nucleic acids, carbohydrates and small molecules. Moreover, it is suitable for ligand fishing and for high capacity capture. Biacore Sensor Chip CM5 also includes couple to carboxyl groups on the sensor surface via -NH2, -SH, -CHO, -OH or –COOH.

Matrix: carboxymethylated dextran covalently attached to a gold surface. Molecules are covalently coupled to the sensor surface via amine, thiol, aldehyde or carboxyl groups. Interactions involving small organic molecules, such as drug candidates, through to large molecular assemblies or whole viruses can be studied. A high binding capacity gives a high response, advantageous for capture assays and for interactions involving small molecules. High surface stability provides accuracy and precision and allows repeated analysis on the same surface.

Article from BIACORE INTERNATIONAL AB

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