HPLC detection tool designed for laboratories

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ESA Biosciences Inc. has announced a new version of its award-winning Corona® Charged Aerosol Detector (CAD™).

The new Corona Plus is an optimised HPLC detection tool designed for laboratories that commonly use THF (Tetrahydrofuran) as a mobile phase component in their chromatographic separations and sample analyses. THF is a commonly used solvent in a number of industries where it is widely used for solubilising and separating various types of polymers.

Now using the Corona Plus - polymer laboratories will be able to benefit from the all-in-one performance benefits that refractive index, low wavelength UV and evaporative light scattering (ELS) detector methods lack. Its superior performance provides ten times the sensitivity of ELS, a broad dynamic range of over four orders of magnitude, more consistent response factors independent of chemical structure, delivering for the first time to HPLC users almost complete universality.

Charged Aerosol Detection is a robust HPLC detection technology that delivers advanced capabilities of interest to every HPLC user-lab. The HPLC column eluent is nebulised and the resulting droplets dry are evaporated at ambient temperature producing analyte particles. A second stream of gas is positively charged as it passes a high-voltage, platinum corona wire. The charged gas collides with and transfers charges to the opposing stream of analyte particles. A negatively charged, low-voltage ion trap removes high-mobility particles while analyte particles transfer their charges to a collector. The charge transferred to the collector is in direct proportion to analyte mass.

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