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Newport Corporation’s Spectra-Physics Lasers Division today introduced its latest, cutting-edge laser tool for basic research and biological imaging – the Mai Tai® DeepSee™. Ideal for applications like multiphoton microscopy, the Mai Tai DeepSee enables researchers and biologists to image deeper without damaging the living tissue sample.

According to Philip G. Smith, Ph.D., Product Manager for Newport’s Spectra-Physics Lasers Division, “Since techniques like multiphoton microscopy were first introduced, researchers have continued to look for ways to penetrate deeper and deeper into living tissue in order to render three dimensional images of living cells. Over the past few years, the average power delivered by ultrafast lasers has increased, and even though this has enabled deeper imaging, the heating effects of these high power lasers often ends up damaging the sample. As a result, many researchers are looking for the capability to deliver shorter, less damaging pulses, while simultaneously increasing fluorescence.”

Smith added, “The main obstacle to delivering shorter pulses to the sample is Group Velocity Dispersion (GVD) and most multiphoton imaging systems installed today experience significant material induced pulse broadening. So, even with laser sources with pulse durations on the order of 100 fs, most imaging systems deliver far broader pulses to the sample.

Smith concluded, “Although, there are well known techniques for overcoming GVD, the complexity and lack of automation of the designs have prevented the vast majority of researchers from implementing them. In order to provide users with a hands-free, out-of-the-box solution, we are very excited to introduce the Mai Tai DeepSee. This new laser is an ideal solution that incorporates automated dispersion compensation and enables biologists to image deeper while preserving the integrity of their living tissue sample.”


The Mai Tai DeepSee features full automation in a compact package. It delivers sufficient GVD compensation at all wavelengths and features a large dynamic range that compensates for all possible objectives and optical systems. Like all Spectra-Physics Mai Tai ultrafast oscillators, the DeepSee has excellent beam pointing stability, excellent beam quality and collimated beam output. The Mai Tai DeepSee also delivers more than 300 nm in useable tuning range with more than 2.5 W of average power.

For more information on the new Mai Tai DeepSee laser, please visit www.newport.com.

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