Category : Bioscience, biotechnology, life health science (precision equipment, instruments, devices and accessories) > Detection equipment, (light scattering detection systems)

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Viscotek (www.viscotek.com) have technical data demonstrating the utility of their unique Low Angle Light Scattering (LALS) detector in directly measuring the molecular weight of large molecules such as polysaccharides.

Unlike multi-angle light scattering techniques that can only determine molecular weight by extrapolation, the LALS technique measures molecular weight directly and thus is inherently more accurate. Consequently the technique is of considerable importance to scientists looking to make routine direct determination of absolute molecular weights of large biomolecules and polymers.

Viscotek's LALS is available as a complete multi-detector (LALS/ Viscometer/ UV/RI) system or as a stand-alone detector that can be coupled to any GPC/SEC system to obtain absolute molecular weights directly. The LALS detector measures scattered light at 7 degrees, close enough to zero that the measurement is direct with no need to extrapolate or calculate as in all other GPC-Light Scattering techniques. This is extremely important when studying large biomolecules such as polysaccharides where the traditional extrapolation using other light scattering instruments gives large data errors.

A technical paper is available providing an unbiased introduction to the theory of light scattering detection and why low angle light scattering measurement is important. The paper is precisely illustrated with examples and proved with mathematical theory. Application papers are also available. For further information on using LALS to make direct molecular weight measurement of large biomolecules contact Viscotek Europe.

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List of all articles in this sub-category Detection equipment, (light scattering detection systems)

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